Database and Softwares
An automatically updated summary of all antibody structures in the Protein Databank. New PDB files processed immediately as they arrive to determine whether they are antibodies and if so, relevant information is extracted and made available on the web.
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An immunohistology database for immunostains that aid in the differential diagnosis of tumors. The database lists antibodies that can differentiate between tumors entered by the user (e.g., lung adenocarcinoma vs. breast carcinoma), ranks the antibodies in terms of their ability to differentiate between the tumors, and then provides instant references to journal articles describing the reactivity of the antibodies. The query system provides a meta-analysis of the literature by utilizing a database developed over several years containing 1800+ peer-reviewed references and over 250,000 immunostain reactivities.
The directory, created by the Antibody Group (ABG), allows a quick access to the antibody structures compiled at PDB. Each PDB entry has a hyperlink to the original source to make full information recovering easy. The VH and VL sequences were aligned and are reported in the VH and VL alignments. The directory will be updated monthly
Listings of HIV specific monoclonal antibodies, maps of binding sites on HIV proteins, sequence alignments showing global variation of linear binding domains, brief descriptions of how the MAb has been used in HIV studies with Medline links, and where to obtain many of the antibodies in the database.
A directory of mouse VH and VK germline segments, part of the webpage of the Antibody Group at the Instituto de Biotecnologia, UNAM (National University of Mexico).
HDB holds data on various aspects of hybridomas and their immunoreactive products. Information on a hybridoma's construction and the reactivity and non-reactivity of its secreted product is included. In addition, information on the availability of an individual hybridoma and its Mab product are included. Information in the HDB is derived from literature, catalogs and survey forms.
An integrated database specialising in Immunoglobulins (Ig), T cell receptors (TcR) and Major Histocompatibility Complex Molecules (MHC) of all species.
A great source of information for molecular biologists and crystallographers on the structure of antibodies. This site also contains the KabatMan database which allows you to search the Kabat sequence database to look for sequence features, AbCheck which lets you test your antibody sequence against the Kabat sequence database to look for unusual features, and Chothia which lets you find canonical assignments for the CDRs in your antibody sequence.
Search "SCOP" for references and structural information on antibodies by keyword or sequence
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